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Published-Ahead-of-Print October 4, 2006, DOI:10.2164/jandrol.106.000372

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Change of Sexual Function in Patients Before and After Ho:YAG Laser Enucleation of the Prostate

Meng FanWei , Gao BaoHua , Fu Qiang , Chen Jun , Liu YuQiang , Shi BenKang , and Xu ZhiShun *

* To whom correspondence should be addressed. E-mail: xuzhishunxinxiang{at}yahoo.com.cn.

Abstract Aim: To evaluate the effect of Ho:YAG laser enucleation of the prostate (HOLEP) to the sexual function of patients with benign prostatic hyperplasia (BPH). METHODS: 108 patients with BPH were recruited and accepted the treatment of HOLEP. The effectiveness of treatment was evaluated by flow rate and the International Prostate Symptom Score (IPSS) before HOLEP and 6 months afterwards. Meanwhile,the sexual functions were evaluated with the Danish Prostate Symptom Score Sexual Function Questionnaire (DanPSS Sex). Results: Before and 6 months after HOLEP treatment, the mean residual urine volume was reduced from 106.0±51.7ml to 5.6±1.7ml(P<0.01). Maximum flow rate(Qmax) was improved from 7.2±3.9 ml/s to 21.7±1.3ml/s(P<0.01),nocturia frequency was reduced from 5.5 to 1.5(P<0.01),the mean IPSS score was decreased from 19.4±5.6 to 7.4±2.6 (P<0.01).The proportion of patients satisfied with their libido were 55% before HOLEP and 57% 6 months afterwards, while 23.5% of the patients have no libido before and after HOLEP.37% of the patients were satisfied with their erection before HOLEP and 40% were after 6 months. 30% of the patients had completely satisfactory sex life before HOLEP, and 32% did 6 months later. The corresponding percentages of fully impotent patients increased from 33% before the procedure to 35% 6 months post operation. Early morning erections were reported by 45% of the patients before the procedure, and by 62% 6 months later(P<0.01). In 70% of the patients with normal sex life ejaculation was retrograde 6 months after HOLEP(P<0.01).Conclusion: HOLEP does not affect the sexual function of patients with BPH but does did improve the ability of early morning erection, and caused retrograde ejaculation.


Key words: Prostate • Surgery • HOLEP • erection • sex function






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Copyright © 2006 by The American Society of Andrology.