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Published-Ahead-of-Print June 2, 2006, DOI:10.2164/jandrol.106.000125

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Obesity and Male Reproductive Potential

Ahmad O. Hammoud , Mark Gibson , C. Matthew Peterson , Blake D. Hamilton , and Douglas T Carrell *

* To whom correspondence should be addressed. E-mail: douglas.carrell{at}hsc.utah.edu.

The incidence of obesity including male obesity is reaching epidemic levels. The alteration in the metabolic and hormonal state created by obesity has been suggested to affect the male reproductive potential. In particular, obesity has been linked to a delay in pubertal sexual maturation and to a specific hormonal profile characterized by increased serum estrogen and decreased androgens levels. Moreover, recent evidence suggested a negative association between obesity and sperm count. The extents by which these changes affect male fertility remain to be uncovered. Finally, the association between obesity and male infertility can be, in rare situation, the expression of underlying genetic or developmental abnormalities.


Key words: Androgen • Hormone • Infertility • Semen • Sperm • obesity






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Copyright © 2006 by The American Society of Andrology.