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Journal of Andrology, Vol 10, Issue 4 283-288, Copyright © 1989 by The American Society of Andrology

JOURNAL ARTICLE

Secretion of plasminogen activator in response to follicle-stimulating hormone in culture medium of human testicular cells from biopsy specimens

Y. Nishimune, K. Sawada, Y. Tajima, D. Watanabe, M. Maekawa, K. Sakamaki, A. Okuyama, M. Nakamura, M. Namiki, K. Matsumoto and al. et
Department of Science for Laboratory Animal Experimentation, Osaka University, Japan.

Testicular cells from human biopsy specimens were cultured and plasminogen activator secreted into the medium was investigated. Follicle stimulating hormone stimulated plasminogen activator secretion. SDS-polyacrylamide gel electrophoresis followed by zymography showed that the molecular weight of plasminogen activator produced by human testicular cells is the same as that of human urokinase. Antigenicity was also found to be of the urokinase type but not of the tissue type.




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Copyright © 1989 by The American Society of Andrology.